Can Smoke Detectors Detect Vape Smoke False positives in vape detectors are a common concern, particularly when the devices are placed in environments with factors that can mimic vaping aerosols., , Common Your guests aren't the only ones checking in. So are their vape pens. With over 13 million regular vapers in the U.S. alone, unauthorized vaping is a major operational risk for hotels. Vape Detector for Schools, Hotels, Home Vape Detector vs. Smoke Detector: Comparison & How They Work