Vaping Increases The Risk of Depression Feeling anxious or low? Vaping may be making it worse. According to Truth Initiative, studies show a strong link between nicotine use and symptoms of anxiety and depression in teens. The If you vape to cope with stress or anxiety, you might be making it worse. Nicotine, a chemical commonly found in vapes and e cigarettes, is addictive and can cause a cycle of Just the Facts: Vaping SAFE Project