E Cigarettes, Vapes, and other Electronic Nicotine Delivery Systems (ENDS) FDA E Cigarettes, Vapes, and other Electronic Nicotine Delivery Systems (ENDS) FDA What is a vape? What does a vape look like? How does the vape actually work? The CDC describes vapes as battery operated devices that heat a liquid containing nicotine to produce an E cigarette, or Vaping Product, Use Associated Lung Injury (EVALI) Fact Sheets Yale Medicine