VAP (Ventilator Associated Pneumonia) Explained Simply for Nurses Ventilator Associated Pneumonia (VAP) is a serious hospital acquired infection that develops 48 hours or more after mechanical ventilation. It significantly increases ICU stay Partners in the Prevention of Ventilator Associated Pneumonia VAP Bundle Ventilator Associated Pneumonia Ventilator Associated Pneumonia ( VAP) is a lung infection that occurs in patients who are on mechanical ventilation for more than 48 hours. A VAP bundle is a set of General flowchart of the study. VAP, ventilator associated pneumonia. Download Scientific Diagram