What You Need to Know About Vaping American Heart Association Vaping vs. Smoking: What's the Nicotine Equivalent? Curious about how vaping compares to smoking? Let's break it down! Disposable Vapes: A typical disposable vape with around 600 puffs can Vaping Equivalents: How Many Puffs of Vape Equal One Cigarette? Smoking vs. Vaping: The Same Damage, Just Marketed Better! If your lungs could talk, they would tell you the harsh truth: Smoking and vaping both burn and damage your lungs, just differently.