Pentose Phosphate Pathway made simple. This pathway has two major jobs: Generate NADPH Produce ribose 5 phosphate NADPH protects cells from oxidative stress and supports fatty acid, cholesterol, steroid, nitric oxide, and respiratory burst The pentose phosphate pathway in health and disease Nature Metabolism Hexose Monophosphate Pathway or Pentose Phosphate Pathway Animations PharmaXChange.info The NADPH Link between the Renin Angiotensin System and the Antioxidant Mechanisms in Dopaminergic Neurons