Pigmented oral lesion in a patient with metastatic melanoma Indian Journal of Dermatology, Venereology and Leprology Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in The metabolic and cardiovascular effects of amphetamine are partially mediated by the central melanocortin system: Cell Reports Medicine Labial melanotic macule
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melanotan 2 blood pressure Relative frequency of solitary melanocytic lesions of the oral mucosa - Buchner - 2004 - Journal of Oral Pathology & Medicine