PROTOCOL OF A PHASE II RANDOMIZED, MULTI CENTER, DOUBLE BLIND, PLACEBO CONTROLLED TRIAL OF S ADENOSYL METHIONINE IN PARTICIPANTS WITH MILD COGNITIVE IMPAIRMENT OR DEMENTIA DUE TO ALZHEIMER'S DISEASE The Journal of Prevention of Alzheimer's Glutathione Synthetase Deficiency as a Cause of Hereditary Hemolytic Disease Glutathione is such a critical soldier in our line of defense that our bodies make it themselves. We even have mechanisms that recycle and reuse it. But what happens when our toxic G6PD Deficiency Glucose 6 phosphate dehydrogenase deficiency X linked recessive disorder Leads to low NADPH, impairing glutathione regeneration RBCs are vulnerable to oxidative damage Pathophysiology: In G6PD deficiency: No