How GHK Peptide Works Signaling GHK acts as a switch for skin repair: Interacts with adenosine receptors reduces inflammation Activates MAPK ERK, PI3K Akt, TGF pathways Stimulates fibroblasts & keratinocytes boosts collagen, elastin By age 30, your skin produces about 25% less collagen. By 40, that number can reach 40%. This decline affects more than just how your skin looks. It changes how it heals, Copper peptide GHK Cu Wikipedia The glycyl l histidyl l lysine Cu2+ tripeptide complex attenuates lung inflammation and fibrosis in silicosis by targeting peroxiredoxin 6 ScienceDirect