What is glutathione? Know as the most important antioxidant in the body, glutathione is an essential antioxidant manufactured in all cells, but primarily in the liver. It is essential because it Glutathione is such an important antioxidant in human physiology, meaning it acts to combat oxidative stress. Strategies for increasing glutathione include: Consume sulfur rich foods like cruciferous vegetables Ensure you get Glutathione Function in the Body Glutathione Depletion in Mitochondrial Diseases Glutathione Reporter