For CKD, I'd separate the proven support from the experimental but interesting category. Astragalus root extract is probably the most tried and true natural compound I'd look at first. There's actual human data showing NAC (N Acetyl L Cysteine) Supplement BrainMD BrainMD Amazon.com: Designs for Health NAC 900mg N Acetyl L Cysteine, Antioxidant Glutathione Precursor Detox + Workout Recovery Support Non GMO + Gluten Free Supplement (120 Capsules) : Health & Household Glutathione specific gammaglutamylcyclotransferase 1 (CHAC1) increases kidney disease risk by modulating ferroptosis Science Translational Medicine
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glutathione or nac better Metabolic Homeostasis of Amino Acids and Diabetic Kidney Disease