Glutathione Peroxidase Proteases Signaling Pathways The Role of the Glutathione System in Stress Adaptation, Morphogenesis and Virulence of Pathogenic Fungi What is glutathione and why must we protect patient access to it? Glutathione peroxidase 4 catalyzed reduction of lipid hydroperoxides in membranes: The polar head of membrane phospholipids binds the enzyme and addresses the fatty acid hydroperoxide group toward the redox center ScienceDirect