Tylenol and Glutathione: Myths Debunked Tylenol, Glutathione, Metals, and Folate Pathways: What Actually Helps Our Kids Myth busting, Acetaminophen version. "Avoid Acetaminophen (Tylenol) because it causes glutathione depletion". Truth?? As a pediatrician and ER doctor and as moms we're often asked about this. And we understand why: Heres why you should avoid Tylenol , First of all, it is full of colorful dyes, sugars, and additives., But the main reason is it depletes glutathione., Glutathione is one of the most