FOXO4 DRI induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53 serine 15 phosphorylation Communications Biology The GHK Cu pen works. But needles at home were never the answer. We took the same clinically backed copper peptide complex and put it into a serum you can use in 30 seconds, Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging: Cell p53 regulated senescence mechanism and role of its modulators in age related disorders ScienceDirect