Ferroptosis: past, present and future Cell Death & Disease Glutathione Depletion Is Necessary for Apoptosis in Lymphoid Cells Independent of Reactive Oxygen Species Formation* Journal of Biological Chemistry The human body is under oxidative stress from a variety of sources at all times. To combat this stress and damage the body utilizes antioxidants of all different varieties. Glutathione is a The glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain Treg cell activation and suppression of antitumor immunity: Cell Reports