Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression: Cancer Cell More research confirming the potential role of glutathione as a driver of cancer growth and spread. Despite the growing body of research, I still see doctors recommending glutathione to patients with active Application of glutathione depletion in cancer therapy: Enhanced ROS based therapy, ferroptosis, and chemotherapy ScienceDirect Glutathione metabolism in cancer progression and treatment resistance Journal of Cell Biology Rockefeller University Press