RLO: The Liver and Drug Metabolism 2: Illustrating the two phases of drug metabolism covered in this Download Scientific Diagram Phase II (Conjugation) Reactions. Introduction Phase I or functionalization reactions do not always produce hydrophilic or pharm Most "detox" reactions aren't detox. They're a traffic jam in your liver. Phase 1 of liver biotransformation cracks fat soluble toxins open using CYP450 enzymes pesticides, hormones, alcohol, plastics, old medications. The
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glutathione conjugation phase 2 Phase II (Conjugation) Reactions. Introduction Phase I or functionalization reactions do not always produce hydrophilic or pharm